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TAK1-Dependent IKK and NF-Kappa-B Activation - Ontify

TAK1-Dependent IKK and NF-Kappa-B Activation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-445989).

Statements about TAK1-Dependent IKK and NF-Kappa-B Activation

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Instance Of

Biological Pathway

Positive Regulation of NF-kappaB Transcription Factor Activity

Part Of

MyD88 Cascade Initiated on Plasma Membrane

MyD88:MAL(TIRAP) Cascade Initiated on Plasma Membrane

TRIF(TICAM1)-Mediated TLR4 Signaling

Toll Like Receptor 3 (TLR3) Cascade

TRAF6 Mediated Induction of NFkB and MAP Kinases upon TLR7/8 or 9 Activation

Interleukin-1 Signaling

Has Part(s)

CHUK, IKBKB and IKBKG Form IKK Complex

Activated TAK1 Mediates Phosphorylation of the IKK Complex

NF-Kappa-B Complex Is Transported From Cytosol to Nucleus

NF-Kappa-B Inhibitor Binds NF-Kappa-B Complex

Active IKBKB Phosphorylates NF-Kappa-B Inhibitor

Ubiquitination of IKBKG by TRAF6

Regulation of NF-Kappa B Signaling

Exact Match

https://identifiers.org/reactome:R-H ...