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TRAF6 Mediated Induction of NFkB and MAP Kinases upon TLR7/8 or 9 Activation

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-975138).

Statements about TRAF6 Mediated Induction of NFkB and MAP Kinases upon TLR7/8 or 9 Activation

Instance Of

Biological Pathway

Has Part(s)

TAK1-Dependent IKK and NF-Kappa-B Activation
MAP Kinase Activation
IRAK2 Mediated Activation of TAK1 Complex upon TLR7/8 or 9 Stimulation

Part Of

MyD88 Dependent Cascade Initiated on Endosome

Exact Match

https://identifiers.org/reactome:R-H ...
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TRAF6 Binds MEKK1
Dissociation of Hp-IRAK1/Or IRAK2:TRAF6-Oligomer From the P-IRAK4 :Oligo-Myd88:activated TLR7/8 or 9 Complex
IRAK1 Recruits IKK Complex upon TLR7/8 or 9 Stimulation