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EXO1 or DNA2 in Complex with BLM or WRN Binds Initially Resected DNA DSBs Along with BRIP1 Recruitment

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5685985).

Statements about EXO1 or DNA2 in Complex with BLM or WRN Binds Initially Resected DNA DSBs Along with BRIP1 Recruitment

Part Of

Instance Of

Biological Process

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

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Processing of DNA Double-Strand Break Ends
P-S990,Ac-K1249-BRIP1 [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
EXO1,DNA2:BLM,WRN [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
3' Short Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
3' Short Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1