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EXO1,DNA2:BLM,WRN [Nucleoplasm] - Ontify
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EXO1,DNA2:BLM,WRN [Nucleoplasm]
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-5685980).
Statements about
EXO1,DNA2:BLM,WRN [Nucleoplasm]
Instance Of
Defined Set
Has Part(s)
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
19 items
ERCC1:XPF Cleaves Flaps Generated by SSA
EXO1 or DNA2 in Complex with BLM or WRN Binds Initially Resected DNA DSBs Along with BRIP1 Recruitment
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Resolution of D-Loops Cleaved by MUS81:EME1 or MUS81:EME2
ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [Nucleoplasm]
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
BLM Mediates Dissolution of Double Holliday Junction
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
3' Short Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [Nucleoplasm]
ATR:ATRIP:p-RPA:DNA DSBs with Annealed 3' SsDNA Overhangs and Displaced Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [Nucleoplasm]
3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [Nucleoplasm]
3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1 [Nucleoplasm]
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C Complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [Nucleoplasm]
Resolution of Holliday Junctions Cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)
ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [Nucleoplasm]
D-Loop Dissociation and Strand Annealing
3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 Mutants (PALB2 Binding):SEM1 [Nucleoplasm]
Defective 3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2 [Nucleoplasm]
DNA2:BLM:TOP3A:RMI1:RMI2 [Nucleoplasm]
Unnamed
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1
EXO1:BLM,WRN [Nucleoplasm]
Unnamed
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1
DNA2:WRN [Nucleoplasm]
Unnamed
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1
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