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P21 RAS:GDP [Plasma Membrane]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-109796).
Statements about
P21 RAS:GDP [Plasma Membrane]
Instance Of
Protein Complex
Has Part(s)
Mature P21 RAS [Plasma Membrane]
Unnamed
:
1
GDP(3−)
Unnamed
:
1
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
67 items
GRB2:SOS:p-Y427-SHC1 Mediated Nucleotide Exchange of RAS
PRKCZ Recruits RAS in Response to Estrogen Stimulation
SOS1-Mediated Nucleotide Exchange of RAS (EGF:EGFR:GRB2:SOS1)
SOS Mediated Nucleotide Exchange of RAS (SHC)
RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and Phosphorylated EGFR:ERBB2 Heterodimers.
PDPK1:PIP3:pS, P-T410 PRKCZ:p21 RAS:GDP [Plasma Membrane]
CD209 Activate GTPase RAS
SOS1-Mediated Nucleotide Exchange of RAS Downstream of FLT3
NMDA-Activated RASGRF1 Activates RAS
Activated FGFR3:p-FRS:p-PTPN11 Activates RAS Nucleotide Exchange
NTRK2 Activates RAS Signaling Through FRS2
SOS-Mediated Nucleotide Exchange on RAS Downstream of PDGFRA Extracellular Domain Dimers
Activated FGFR1:p-SHC1:GRB2:SOS1 Activates RAS Nucleotide Exchange
Activated FGFR2:p-SHC1:GRB2:SOS1 Activates RAS Nucleotide Exchange
RAS Guanyl Nucleotide Exchange by MET-Bound GRB2:SOS1
Activated FGFR1:p-FRS:p-PTPN11 Activates RAS Nucleotide Exchange
Activated FGFR3:p-SHC1:GRB2:SOS1 Activates RAS Nucleotide Exchange
P-KIT Mutants:GRB2:SOS Catalyzes Nucleotide Exchange on RAS
Activated FGFR3 Point, Translocation and Fusion Mutants:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with P-EGFRvIII)
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 KD Mutants
SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with Phosphorylated SHC1 and P-EGFRvIII)
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 KD Mutants and EGFR
RAS Guanyl Nucleotide Exchange Mediated by the P-6Y- ERBB2 ECD Mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1
Mature P21 RAS Binds GDP
Intrinsic Nucleotide Exchange on RAS
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 ECD Mutants and EGFR Through GRB2
SOS1-Mediated Nucleotide Exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)
RAS Intrinsic GTPase Activity Hydrolyzes GTP to GDP
SOS-Mediated Nucleotide Exchange of RAS Downstream of Mutant PDGFR Receptors
RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and ERBB2 Homodimer:p-SHC1
Activated FGFR2:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
Activated FGFR3:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with Ligand-Responsive P-6Y-EGFR Mutants)
RAS Guanyl Nucleotide Exchange by SOS1 Bound to GRB2, SCH1-2 and MET
Activated FGFR4 Mutants:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
Activated FGFR2 Mutants:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with Phosphorylated SHC1 and Ligand-Responsive P-6Y-EGFR Mutants)
RAS GAPs Stimulate RAS GTPase Activity
Activation of RAS by P-KIT Bound SOS1
Activated FGFR1:p-FRS:GRB2:SOS1 Activates RAS Nucleotide Exchange
P-RasGRP1,3:DAG Cause RAS to Exchange GDP for GTP
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 Mediates Exchange of GTP for GDP Bound to RAS
Activated FGFR4:p-SHC1:GRB2:SOS1 Activates RAS Nucleotide Exchange
Activated FGFR4:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
GRB2-1:SOS1:p-Y-SHC Mediated Nucleotide Exchange of RAS
SOS-Mediated Nucleotide Exchange on RAS (PDGF Receptor:GRB2:SOS)
GRB2:SOS1:p-Y-IRS1,p-Y-IRS2 Mediated Nucleotide Exchange of RAS
RAS Guanyl Nucleotide Exchange Mediated by SOS1 Bound to GRB2 in Complex with Phosphorylated ERBB4:ERBB2 Heterodimers
Sos-Mediated Nucleotide Exchange of Ras (Tie2 Receptor:Grb2:Sos)
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants
NCAM1:pFAK:Grb2:Sos-Mediated Nucleotide Exchange of Ras
NTRK2 Activates RAS Signaling Through SHC1
RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and P-SHC1:Phosphorylated ERBB2 Heterodimers
RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and P-Y349,350-SHC1:p-ERBB4
GRB2-1:SOS1:p-3Y-SHC1 Mediated Nucleotide Exchange of RAS
RAS Activation by SOS1 Bound to Phosphorylated Heterodimers of ERBB2 TMD/JMD Mutants and EGFR
Activated FGFR2:p-FRS:p-PTPN11 Activates RAS Nucleotide Exchange
RASA1 Stimulates RAS GTPase Activity
Activated FGFR4:p-FRS:p-PTPN11 Activates RAS Nucleotide Exchange
SOS1-Mediated Nucleotide Exchange of RAS (HB-EFG-Initiated)
Activated FGFR1 Mutants:p-FRS2:GRB2:SOS1 Activates RAS Nucleotide Exchange
NTRK3 Activates RAS Through SHC1
RAS GEFs Promote RAS Nucleotide Exchange
RAS Guanyl Nucleotide Exchange by SOS1 Associated with RANBP9 and MET
SOS1-Mediated Nucleotide Exchange of RAS Downstream of FLT3 Fusion Mutants
FLT3 Mutants:GRB2:SOS1-Mediated Nucleotide Exchange on RAS
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