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SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with Phosphorylated SHC1 and P-EGFRvIII)

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5637808).

Statements about SOS-Mediated Nucleotide Exchange of RAS (Mediated by GRB2:SOS1 in Complex with Phosphorylated SHC1 and P-EGFRvIII)

Instance Of

Biological Process

Part Of

Constitutive Signaling by EGFRvIII

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

P21 RAS:GDP [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
P21 RAS:GTP [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1
GTP(4−)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
GDP(3−)
Object of Statement Has Role
:
Product
Unnamed
: 1
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P-5Y-EGFRvIII:p-Y349,Y350-SHC1:GRB2:SOS1 [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1