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RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and Phosphorylated EGFR:ERBB2 Heterodimers.

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1250498).

Statements about RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and Phosphorylated EGFR:ERBB2 Heterodimers.

Instance Of

Biological Process

Part Of

GRB2 Events in ERBB2 Signaling

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

P21 RAS:GDP [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
P21 RAS:GTP [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
GTP(4−)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
GDP(3−)
Object of Statement Has Role
:
Product
Unnamed
: 1
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