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RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and P-SHC1:Phosphorylated ERBB2 Heterodimers
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1250463).
Statements about
RAS Guanyl-Nucleotide Exchange Mediated by SOS1 in Complex with GRB2 and P-SHC1:Phosphorylated ERBB2 Heterodimers
Instance Of
Biological Process
Part Of
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
GTP(4−)
Object of Statement Has Role
:
Reactant
Unnamed
:
1
P21 RAS:GTP [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
:
1
GDP(3−)
Object of Statement Has Role
:
Product
Unnamed
:
1
P21 RAS:GDP [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 Heterodimers [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
SHC1 Events in ERBB2 Signaling
