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MDM2 Ubiquitinates TP53
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6804879).
Statements about
MDM2 Ubiquitinates TP53
Instance Of
Biological Process
Part Of
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Ub [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
:
12
Stabilization of P53
Oxidative Stress Induced Senescence
Regulation of TP53 Degradation
P14ARF:p-S166,S188-MDM2 Dimer,p-S166,S188-MDM2:MDM4 [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
PolyUb-TP53 Tetramer [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
:
1
P-S166,S188-MDM2 Dimer, P-S166,S188-MDM2:MDM4 [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
:
1
P-S166,S188-MDM2 Dimer, P-S166,S188-MDM2,MDM4:TP53 [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
P-S166,S188-MDM2 Dimer, P-S166,S188-MDM2,MDM4:TP53 [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
Oncogene Induced Senescence
