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Stabilization of P53

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-69541).

Statements about Stabilization of P53

Instance Of

Biological Pathway

Part Of

P53-Dependent G1 DNA Damage Response

Has Part(s)

11 items
Autodegradation of the E3 Ubiquitin Ligase COP1
Ubiquitinated TP53 Translocates to the Cytosol
MDM2 Ubiquitinates Phosphorylated MDM4
Phosphorylation of MDM4 by CHEK2
Phosphorylation of MDM4 by ATM
MDM2 Binds TP53
ATM Phosphorylates TP53 at S15
MDM2 Forms Homo- or Heterodimers
CHEK2 Phosphorylates TP53
MDM2 Ubiquitinates TP53
ATM Phosphorylates MDM2

Exact Match

https://identifiers.org/reactome:R-H ...
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