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P-S317,S345-CHEK1 [Nucleoplasm]

Instance of entity with accessioned sequence in Homo sapiens with Reactome ID (R-HSA-113838).

Statements about P-S317,S345-CHEK1 [Nucleoplasm]

Subclass Of

Checkpoint Kinase 1

Has Part(s)

O-Phospho-L-Serine
Series Ordinal
:317
O-Phospho-L-Serine
Series Ordinal
:345

Exact Match

https://identifiers.org/reactome:R-H ...

Part Of

11 items
Recruitment and Activation of Chk1
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E2F6 Binds RAD51 Gene Promoter
E2F6 Binds RRM2 Gene Promoter
Phosphorylation of Cdc25C at Ser 216 by Chk1
CHEK1 Phosphorylates E2F6
CHEK1 Phosphorylates BRCA2
CHEK1 Phosphorylates TP53
Activation of CHEK1 at Resected DNA DSBs
Phosphorylation of Wee1 Kinase by Chk1
CHEK1 Phosphorylates RAD51
Phosphorylation of Cdc25A at Ser-123 by Chk1