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Activation of CHEK1 at Resected DNA DSBs - Ontify
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Activation of CHEK1 at Resected DNA DSBs
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5684887).
Statements about
Activation of CHEK1 at Resected DNA DSBs
Part Of
Processing of DNA Double-Strand Break Ends
Instance Of
Biological Process
DNA Replication
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
ATP(4-)
ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [Nucleoplasm]
ADP(3-)
ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [Nucleoplasm]
P-S317,S345-CHEK1 [Nucleoplasm]
P-T916,S945-CLSPN [Nucleoplasm]
TIMELESS:TIPIN [Nucleoplasm]
ATR:ATRIP:p-RPA:3' Overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C Complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [Nucleoplasm]
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