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Phosphorylation of IRF-3/IRF7 and Their Release From the Activated TLR Complex
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-166245).
Statements about
Phosphorylation of IRF-3/IRF7 and Their Release From the Activated TLR Complex
Instance Of
Biological Process
Part Of
Activation of IRF3/IRF7 Mediated by TBK1/IKK Epsilon
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKE:IRF3/IRF7 [Endosome Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
ATP(4-)
Object of Statement Has Role
:
Reactant
Unnamed
:
6
Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane]
Object of Statement Has Role
:
Product
Unnamed
:
1
ADP(3-)
Object of Statement Has Role
:
Product
Unnamed
:
6
P-4S,T404-IRF3,p-S477,S479-IRF7 [Cytosol]
Object of Statement Has Role
:
Product
Unnamed
:
2
Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKE:IRF3/IRF7 [Endosome Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
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