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Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane] - Ontify
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Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-936970).
Statements about
Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKi [Endosome Membrane]
Instance Of
Protein Complex
Has Part(s)
Activated TBK1/IKK Epsilon [Cytosol]
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [Endosome Membrane]
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
Phosphorylation of IRF-3/IRF7 and Their Release From the Activated TLR Complex
IRF3/IRF7 Recruitment to P-TBK1/P-IKK Epsilon Bound to the Activated TLR4
Activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/P-IKKE:IRF3/IRF7 [Endosome Membrane]
Recruitment of TBK1/IKK Epsilon to K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR4 Followed by Their Phosphorylation
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