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IRAK2 Mediated Activation of TAK1 Complex
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-937042).
Statements about
IRAK2 Mediated Activation of TAK1 Complex
Instance Of
Biological Pathway
Part Of
MyD88 Cascade Initiated on Plasma Membrane
MyD88:MAL(TIRAP) Cascade Initiated on Plasma Membrane
Has Part(s)
IRAK2 Induces TRAF6 Oligomerization
Auto Ubiquitination of Oligo-TRAF6 Bound to P-IRAK2
Activated TRAF6 Synthesizes Unanchored Polyubiquitin Chains
Activated TRAF6:p-IRAK2 Interacts with TAK1 Complex
Auto Phosphorylation of TAK1 Bound to P-IRAK2:pUb Oligo-TRAF6: Free K63 pUb:TAB1:TAB2/TAB3
Exact Match
https://identifiers.org/reactome:R-H ...
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