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Phosphorylation and Activation of CHEK2 by ATM - Ontify

Phosphorylation and Activation of CHEK2 by ATM

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-69891).

Statements about Phosphorylation and Activation of CHEK2 by ATM

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Part Of

G2/M DNA Damage Checkpoint

Recruitment and ATM-Mediated Phosphorylation of Repair and Signaling Proteins at DNA Double Strand Breaks

Instance Of

Biological Process

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A Complex:CHEK2 [Nucl...

DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A Complex [Nucleoplasm]

P-T68-CHEK2 [Nucleoplasm]

DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:p-S25,S1778-TP53BP1:p-4S,2T-BRCA1-A Complex:CHEK2 [Nucl...

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Object of Statement Has Role

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Object of Statement Has Role

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Object of Statement Has Role

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Object of Statement Has Role

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Object of Statement Has Role

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