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G2/M DNA Damage Checkpoint - Ontify

G2/M DNA Damage Checkpoint

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-69473).

Statements about G2/M DNA Damage Checkpoint

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Instance Of

Biological Pathway

Part Of

G2/M Checkpoints

Has Part(s)

Chk1/Chk2(Cds1) Mediated Inactivation of Cyclin B:Cdk1 Complex

Recruitment and Activation of Chk1

CHEK1 Phosphorylates TP53

Phosphorylation and Activation of CHEK2 by ATM

P-T68-CHEK2 Dimerizes

CHEK2 Is Recruited to DNA DSBs

P-T68-CHEK2 Autophosphorylates

ATR Phosphorylates TP53

Exact Match

https://identifiers.org/reactome:R-H ...