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Chk1/Chk2(Cds1) Mediated Inactivation of Cyclin B:Cdk1 Complex - Ontify

Chk1/Chk2(Cds1) Mediated Inactivation of Cyclin B:Cdk1 Complex

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-75035).

Statements about Chk1/Chk2(Cds1) Mediated Inactivation of Cyclin B:Cdk1 Complex

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Part Of

G2/M DNA Damage Checkpoint

Instance Of

Biological Pathway

Has Part(s)

Phosphorylation of Cdc25C at Ser216 by CHEK2

Association of P-S216-CDC25C with 14-3-3 Proteins

Phosphorylation of Wee1 Kinase by Chk1

Wee1-Mediated Phosphorylation of Cyclin B1:phospho-Cdc2 Complexes

P-S216-CDC25C Translocates to the Cytosol

Exact Match

https://identifiers.org/reactome:R-H ...