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PP2A Dephosphorylates AXIN, APC and CTNNB1 in the Destruction Complex - Ontify
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PP2A Dephosphorylates AXIN, APC and CTNNB1 in the Destruction Complex
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-3601585).
Statements about
PP2A Dephosphorylates AXIN, APC and CTNNB1 in the Destruction Complex
Instance Of
Biological Process
Part Of
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
P-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-Ub-APC (20 Aa Repeat Region):PP2A:AMER1 Complex [Cytosol]
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 Complex [Cytosol]
P-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-Ub-APC (20 Aa Repeat Region):PP2A:AMER1 Complex [Cytosol]
Object of Statement Has Role
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Reactant
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1
Object of Statement Has Role
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Product
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Object of Statement Has Role
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Modifier
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Disassembly of the Destruction Complex and Recruitment of AXIN to the Membrane