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Disassembly of the Destruction Complex and Recruitment of AXIN to the Membrane - Ontify
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Disassembly of the Destruction Complex and Recruitment of AXIN to the Membrane
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-4641262).
Statements about
Disassembly of the Destruction Complex and Recruitment of AXIN to the Membrane
Instance Of
Biological Pathway
Part Of
TCF Dependent Signaling in Response to WNT
Has Part(s)
PP2A Dephosphorylates AXIN, APC and CTNNB1 in the Destruction Complex
DVL Recruits GSK3beta:AXIN1 to the Receptor Complex
Phosphorylation of LRP5/6 Cytoplasmic Domain by Membrane-Associated GSK3beta
Phosphorylation of LRP5/6 Cytoplasmic Domain by CSNKI
Beta-Catenin Is Released From the Destruction Complex
Exact Match
https://identifiers.org/reactome:R-H ...
FRAT Proteins Bind GSK3beta
WNT3A Stimulates the Caveolin-Dependent Internalization of FZD5:p-LRP6
Beta-Catenin Destruction Complex Disassembly