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Decay of mRNA in SMG6:SMG5:SMG7:mRNA Complex

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-927830).

Statements about Decay of mRNA in SMG6:SMG5:SMG7:mRNA Complex

Instance Of

Biological Process

Part Of

Nonsense Mediated Decay (NMD) Enhanced by the Exon Junction Complex (EJC)

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

11 items
MRNA Cleaved by SMG6 [Cytosol]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
Cap Binding Complex (CBC) [Cytosol]
Object of Statement Has Role
:
Product
Unnamed
: 1
Eukaryotic Translation Initiation Factor 4 Gamma 1
Object of Statement Has Role
:
Product
Unnamed
: 1
Poly(A) Binding Protein Cytoplasmic 1
Object of Statement Has Role
:
Product
Unnamed
: 1
PP2A (Aalpha:B55alpha:Calpha) [Cytosol]
Object of Statement Has Role
:
Product
Unnamed
: 1
SMG5 Nonsense Mediated mRNA Decay Factor
Object of Statement Has Role
:
Product
Unnamed
: 1
SMG6 Nonsense Mediated mRNA Decay Factor
Object of Statement Has Role
:
Product
Unnamed
: 1
SMG7 Nonsense Mediated mRNA Decay Factor
Object of Statement Has Role
:
Product
Unnamed
: 1
UPF1 RNA Helicase and ATPase
Object of Statement Has Role
:
Product
Unnamed
: 1
P-4S-UPF1 [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
PP2A (Aalpha:B55alpha:Calpha) [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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