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Hh Processing Variants Are Translocated to the Cytosol in a VCP-Dependent Manner

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5387389).

Statements about Hh Processing Variants Are Translocated to the Cytosol in a VCP-Dependent Manner

Instance Of

Biological Process

Part Of

Hh Mutants Are Degraded by ERAD

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

ATP(4-)
Object of Statement Has Role
:
Reactant
Unnamed
: 6
Water
Object of Statement Has Role
:
Reactant
Unnamed
: 6
Ub-SHH Processing Variants:ERLEC:OS9:SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
ADP(3-)
Object of Statement Has Role
:
Product
Unnamed
: 6
OS9/ERLEC1 [Endoplasmic Reticulum Quality Control Compartment]
Object of Statement Has Role
:
Product
Unnamed
: 1
Phosphate(3−) Ion
Object of Statement Has Role
:
Product
Unnamed
: 6
SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1
Ub-SHH Variants [Cytosol]
Object of Statement Has Role
:
Product
Unnamed
: 1
Ub-SHH Processing Variants:ERLEC:OS9:SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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