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SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane] - Ontify
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SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-5362378).
Statements about
SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Instance Of
Protein Complex
Has Part(s)
Derlin 2
SEL1L Adaptor Subunit of ERAD E3 Ubiquitin Ligase
SYVN1 Dimer [Endoplasmic Reticulum Membrane]
VCP Hexamer [Cytosol]
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
Ub-SHH Processing Variants:ERLEC:OS9:SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
C-Terminal Hh Fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
VCP-Catalyzed ATP Hydrolysis Promotes the Translocation of Hh-C Into the Cytosol
Hh Processing Variants Are Recruited to SEL1:SYVN at the ER Membrane
Ub-C-Terminal Hh Fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
SHH Processing Variants:ERLEC:OS9:SEL1:SYVN1 Dimer:DERL2:VCP Hexamer [Endoplasmic Reticulum Membrane]
Hh Processing Variants Are Translocated to the Cytosol in a VCP-Dependent Manner
C-Terminal Hh Fragments Are Recruited to SEL1:SYVN1 at the ER Membrane
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