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Covalent Tyrosine Kinase Inhibitors Bind and Inactivate EGFR Kinase Domain Mutant Dimers Resistant to Non-Covalent Tyrosine Kinase Inhibitors - Ontify
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Covalent Tyrosine Kinase Inhibitors Bind and Inactivate EGFR Kinase Domain Mutant Dimers Resistant to Non-Covalent Tyrosine Kinase Inhibitors
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1220611).
Statements about
Covalent Tyrosine Kinase Inhibitors Bind and Inactivate EGFR Kinase Domain Mutant Dimers Resistant to Non-Covalent Tyrosine Kinase Inhibitors
Instance Of
Biological Process
Part Of
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Covalent EGFR Tyrosine Kinase Inhibitors [Cytosol]
Resistant Ligand-Responsive EGFR Mutants [Plasma Membrane]
Resistant Ligand-Responsive EGFR Mutants:Covalent EGFR TKIs [Plasma Membrane]
Object of Statement Has Role
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Reactant
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Object of Statement Has Role
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Reactant
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Object of Statement Has Role
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Product
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