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Non-Covalent Tyrosine Kinase Inhibitors Bind and Inactivate Sensitive Ligand-Responsive EGFR Cancer Mutants
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1220610).
Statements about
Non-Covalent Tyrosine Kinase Inhibitors Bind and Inactivate Sensitive Ligand-Responsive EGFR Cancer Mutants
Instance Of
Biological Process
Part Of
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Active Dimers of Ligand-Responsive EGFR Mutants [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
Resistant Ligand-Responsive EGFR Mutants [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
:
1
Non-Covalent EGFR Tyrosine Kinase Inhibitors [Cytosol]
Object of Statement Has Role
:
Reactant
Unnamed
:
2
Sensitive Ligand-Responsive EGFR Mutants:Non-Covalent EGFR TKIs [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
:
1