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Non-Covalent Tyrosine Kinase Inhibitors Bind and Inactivate Sensitive Ligand-Responsive EGFR Cancer Mutants

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1220610).

Statements about Non-Covalent Tyrosine Kinase Inhibitors Bind and Inactivate Sensitive Ligand-Responsive EGFR Cancer Mutants

Instance Of

Biological Process

Part Of

Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

Active Dimers of Ligand-Responsive EGFR Mutants [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
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Resistant Ligand-Responsive EGFR Mutants [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1
Non-Covalent EGFR Tyrosine Kinase Inhibitors [Cytosol]
Object of Statement Has Role
:
Reactant
Unnamed
: 2
Sensitive Ligand-Responsive EGFR Mutants:Non-Covalent EGFR TKIs [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1