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POLQ Extends Annealed 3'-ssDNA Overhangs in MMEJ
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5687640).
Statements about
POLQ Extends Annealed 3'-ssDNA Overhangs in MMEJ
Part Of
HDR Through MMEJ (Alt-NHEJ)
Instance Of
Biological Process
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Annealed Microhomologous 3'-ssDNA Overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
2'-Deoxyribonucleoside Triphosphate
Object of Statement Has Role
:
Reactant
Unnamed
:
1
Extended Microhomologous 3'-ssDNA Overhangs-Flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
:
1
Annealed Microhomologous 3'-ssDNA Overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
Diphosphate(3−) Anion
Object of Statement Has Role
:
Product
Unnamed
:
1
RAD52 Heptamer [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
BRCA2 DNA Repair Associated
Object of Statement Has Role
:
Modifier
Unnamed
:
1