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POLQ Extends Annealed 3'-ssDNA Overhangs in MMEJ

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5687640).

Statements about POLQ Extends Annealed 3'-ssDNA Overhangs in MMEJ

Part Of

HDR Through MMEJ (Alt-NHEJ)

Instance Of

Biological Process

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

Annealed Microhomologous 3'-ssDNA Overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
2'-Deoxyribonucleoside Triphosphate
Object of Statement Has Role
:
Reactant
Unnamed
: 1
Extended Microhomologous 3'-ssDNA Overhangs-Flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
Annealed Microhomologous 3'-ssDNA Overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
Diphosphate(3−) Anion
Object of Statement Has Role
:
Product
Unnamed
: 1
RAD52 Heptamer [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
BRCA2 DNA Repair Associated
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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