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HDR Through MMEJ (Alt-NHEJ) - Ontify
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HDR Through MMEJ (Alt-NHEJ)
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5685939).
Statements about
HDR Through MMEJ (Alt-NHEJ)
Instance Of
Biological Pathway
Part Of
Homology Directed Repair
Has Part(s)
MRN Complex Binds RBBP8
MRN and RBBP8 Resect DNA DSBs in MMEJ
PARP1 or PARP2, FEN1 and POLQ Are Recruited to MMEJ Site
POLQ Extends Annealed 3'-ssDNA Overhangs in MMEJ
PARP1,PARP2 Dimers Bound to MMEJ Sites autoPARylate
FEN1 Cleaves Displaced ssDNA Flaps During MMEJ
MRN Recruits LIG3:XRCC1 to MMEJ Sites
LIG3 Ligates Remaining SSBs in MMEJ
Exact Match
https://identifiers.org/reactome:R-H ...