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PARP1,PARP2 Dimers and FEN1 Bind POLB and Displace APEX1 From Damaged AP Site - Ontify

PARP1,PARP2 Dimers and FEN1 Bind POLB and Displace APEX1 From Damaged AP Site

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5649873).

Statements about PARP1,PARP2 Dimers and FEN1 Bind POLB and Displace APEX1 From Damaged AP Site

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Part Of

POLB-Dependent Long Patch Base Excision Repair

Instance Of

Biological Process

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

Flap Structure-Specific Endonuclease 1

PARP1,PARP2 Dimers [Nucleoplasm]

POLB:APEX1:SSB(3'dNMP-Displaced 5'ddRP)-dsDNA [Nucleoplasm]

DNA-(apurinic or Apyrimidinic Site) Lyase

PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-Displaced 5'ddRP)-dsDNA [Nucleoplasm]

Poly(ADP-Ribose) Glycohydrolase

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Object of Statement Has Role

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