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Energy Dependent Regulation of mTOR by LKB1-AMPK - Ontify

Energy Dependent Regulation of mTOR by LKB1-AMPK

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-380972).

Statements about Energy Dependent Regulation of mTOR by LKB1-AMPK

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Instance Of

Biological Pathway

Regulation of Cell Cycle

Part Of

MTOR Signalling

Has Part(s)

P-AMPK Phosphorylates TSC1:TSC2

RHEB in mTORC1:RHEB:GTP Hydrolyses GTP

Activation of Cytosolic AMPK by Phosphorylation

AMPK Is Dephosphorylated

Phosphorylated AMPK Binds AMP

AMPK Phosphorylates Raptor in the mTORC1 Complex

Exact Match

https://identifiers.org/reactome:R-H ...

LKB1 Forms a Trimeric Complex with STRAD and MO25