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MTOR Signalling - Ontify

MTOR Signalling

MTOR Signaling

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-165159).

Statements about MTOR Signalling

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Instance Of

Biological Pathway

Part Of

Signal Transduction

Has Part(s)

15 items

Inhibition of TSC Complex Formation by PKB

MTORC1-Mediated Signalling

Energy Dependent Regulation of mTOR by LKB1-AMPK

GTP Loading by Rheb

Rag Dimer Formation

Formation of Ragulator Complex

Ragulator Binds Rag Dimers

SLC38A9 Binds Ragulator:Rag Dimers

SLC38A9 Transports L-Arg From Lysosomal Lumen to Cytosol

Ragulator:Rag Dimers:SLC38A9 Bind mTORC1

Formation of Active mTORC1 Complex

AKT1S1 (PRAS40) Binds mTORC1

Activated Akt1 Phosphorylates AKT1S1 (PRAS40)

Phosphorylated AKT1S1:mTORC1 Binds YWHAB

MTORC1 Phosphorylates AKT1S1

Exact Match

https://identifiers.org/reactome:R-H ...