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Degradation of GLI1 by the Proteasome
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5610780).
Statements about
Degradation of GLI1 by the Proteasome
Instance Of
Biological Pathway
Part Of
Hedgehog 'Off' State
Has Part(s)
Exact Match
https://identifiers.org/reactome:R-H ...
SCF(beta-TrCP) Ubiquitinates P-GLI1
NUMB:ITCH Bind and Ubiquitnate GLI1
GLI1 Is Degraded by the Proteasome After Ubiquitination by Beta-TrCP
GLI1 Is Degraded by the Proteasome After Ubiquitination by ITCH
NUMB Binds ITCH
PKA Phosphorylates GLI1
