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TRAF3-Dependent IRF Activation Pathway
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-918233).
Statements about
TRAF3-Dependent IRF Activation Pathway
Instance Of
Biological Pathway
Part Of
DDX58/IFIH1-Mediated Induction of Interferon-Alpha/Beta
Has Part(s)
11 items
Exact Match
https://identifiers.org/reactome:R-H ...
TBK1/IKK Epsilon Complex Interacts with MAVS Bound TRAF3
Recruitment of TRAF3 to MAVS
Recruitment of IRF3,IRF7
Translocation of Phosphorylated IRF3,IRF7 Dimers Into Nucleus
CREBBP, EP300 Binds P-T,4S-IRF3:p-T,4S-IRF3
Dimerization of Phospho IRF3 or Phospho IRF7
Phosphorylation and Release of IRF3/IRF7
P-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 Binds Promoters of Interferon-Beta
Expression of Interferon-Beta
TBK1, IKBKE Are Autophosphorylated at Ser172
TBK1 or IKBKE Forms Homodimers
