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DDX58/IFIH1-Mediated Induction of Interferon-Alpha/Beta - Ontify
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DDX58/IFIH1-Mediated Induction of Interferon-Alpha/Beta
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-168928).
Statements about
DDX58/IFIH1-Mediated Induction of Interferon-Alpha/Beta
Instance Of
Biological Pathway
Has Part(s)
12 items
TRAF3-Dependent IRF Activation Pathway
TRAF6 Mediated IRF7 Activation
TRAF6 Mediated NF-kB Activation
Negative Regulators of DDX58/IFIH1 Signaling
Viral dsRNA:IFIH1, Viral dsRNA:K63polyUb-DDX58 Bind MAVS
Viral dsRNA Binds IFIH1:TKFC
DDX58 Is K63 Polyubiquitinated
HSP90 Binds TBK1 and IRF3
MAVS:TOMM70 Recruits HSP90:TBK1:IRF3
Part Of
Innate Immune System
Exact Match
https://identifiers.org/reactome:R-H ...
MAVS Binds TOMM70
NF-kB Activation Through FADD/RIP-1 Pathway Mediated by Caspase-8 and -10
Viral dsRNA Binds DDX58
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