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CDK8 Phosphorylates NICD1 PEST Domain Mutants

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2220971).

Statements about CDK8 Phosphorylates NICD1 PEST Domain Mutants

Instance Of

Biological Process

Part Of

Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

11 items
ATP(4-)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
ADP(3-)
Object of Statement Has Role
:
Product
Unnamed
: 1
CDK8:CCNC [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
CREB Binding Protein
Object of Statement Has Role
:
Product
Unnamed
: 1
E1A Binding Protein P300
Object of Statement Has Role
:
Product
Unnamed
: 1
MAML [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
P-NICD1 PEST Domain Mutants [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
PCAF [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
RBPJ:SNW1 [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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