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Mandelate 4-Monooxygenase Activity

Mandelic Acid 4-Hydroxylase Activity

Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.

Statements about Mandelate 4-Monooxygenase Activity

Subclass Of

Exact Match

http://purl.obolibrary.org/obo/GO_00 ...
https://www.rhea-db.org/rhea/21716

Instance Of

Molecular Function

Has Part(s)

Dioxygen
Part Of
:
Left Side of Reaction
Water
Part Of
:
Right Side of Reaction
(S)-4-Hydroxymandelate
Part Of
:
Right Side of Reaction
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(6R)-L-Erythro-6,7-Dihydrobiopterin
Part Of
:
Right Side of Reaction
Sapropterin
Part Of
:
Left Side of Reaction
(S)-Mandelate
Part Of
:
Left Side of Reaction
Oxidoreductase Activity, Acting on Paired Donors, with Incorporation or Reduction of Molecular Oxygen, Reduced Pteridine as One Donor, and Incorporation of One Atom of Oxygen