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2-Isopropylmalate Synthase Activity

GO:0003852

Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).

Statements about 2-Isopropylmalate Synthase Activity

Subclass Of

Acyltransferase, Acyl Groups Converted Into Alkyl on Transfer

Exact Match

http://purl.obolibrary.org/obo/GO_00 ...
https://www.rhea-db.org/rhea/21524

Instance Of

Molecular Function

Has Part(s)

3-Methyl-2-Oxobutanoate
Part Of
:
Left Side of Reaction
Water
Part Of
:
Left Side of Reaction
Acetyl-CoA(4-)
Part Of
:
Left Side of Reaction
Coenzyme A(4-)
Part Of
:
Right Side of Reaction
Hydron
Part Of
:
Right Side of Reaction
(2S)-2-Isopropylmalate(2-)
Part Of
:
Right Side of Reaction
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