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Deoxyhypusine Synthase Activity

EIF5A-Precursor-Lysine:spermidine 4-Aminobutyltransferase (Propane-1,3-Diamine-Forming) Activity

Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+.

Statements about Deoxyhypusine Synthase Activity

Subclass Of

Transferase Activity, Transferring Alkyl or Aryl (Other than Methyl) Groups

Exact Match

http://purl.obolibrary.org/obo/GO_00 ...
https://www.rhea-db.org/rhea/33299

Instance Of

Molecular Function

Has Part(s)

Spermidine(3+)
Part Of
:
Left Side of Reaction
Trimethylenediaminium
Part Of
:
Right Side of Reaction
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