Ubiquitin-Dependent ERAD Pathway

Ubiquitin-Dependent Proteasomal Protein Catabolism of ER Proteins

The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the.