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Inactivation of CSF3 (G-CSF) Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9705462).
Statements about
Inactivation of CSF3 (G-CSF) Signaling
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Biological Pathway
Has Part(s)
P-Y-STAT1,3,5 Dimer Binds SOCS1 Gene
P-Y-STAT1,3,5 Dimer Binds SOCS3 Gene
P-Y-STAT1,3,5 Dimer Enhances Expression of SOCS1
P-Y-STAT1,3,5 Dimer Enhances Expression of SOCS3
SOCS1,3 Binds P-4Y-CSF3R:CSF3 Dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2
SOCS1,3:p-4Y-CSF3R:CSF3 Dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 Is Endocytosed
SOCS1,3:p-4Y-CSF3R:CSF3 Dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 Binds CUL5, ELOB, ELOC, RNF7
SOCS1,3 Ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 Dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7
CSF3 Dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 Translocates From the Endocytic Vesicle Membrane to the Lysosomal Membrane
Part Of
Signaling by CSF3 (G-CSF)
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