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PI3K Bound to Phosphorylated Heterodimers of ERBB2 ECD Mutants and EGFR Converts PIP2 to PIP3

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9665407).

Statements about PI3K Bound to Phosphorylated Heterodimers of ERBB2 ECD Mutants and EGFR Converts PIP2 to PIP3

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process

Has Part(s)

ATP(4-)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
ADP(3-)
Object of Statement Has Role
:
Product
Unnamed
: 1
P-6Y-ERBB2 ECD Mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
1-Phosphatidyl-1D-Myo-Inositol 4,5-Bisphosphate(5-)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
1-Phosphatidyl-1D-Myo-Inositol 3,4,5-Trisphosphate(7-)
Object of Statement Has Role
:
Product
Unnamed
: 1

Part Of

Signaling by ERBB2 ECD Mutants
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