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P-6Y-ERBB2 ECD Mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [Plasma Membrane] - Ontify
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P-6Y-ERBB2 ECD Mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [Plasma Membrane]
Instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-9665453).
Statements about
P-6Y-ERBB2 ECD Mutants:EGF:p-6Y-EGFR:GRB2:GAB1:PI3K [Plasma Membrane]
Exact Match
https://identifiers.org/reactome:R-H ...
Instance Of
Protein Complex
Has Part(s)
P-6Y-ERBB2 ECD Mutants:EGF:p-6Y-EGFR:GRB2:GAB1 [Plasma Membrane]
PIK3CA:PIK3R1 [Cytosol]
Part Of
Phosphorylated Heterodimers of ERBB2 ECD Mutants and EGFR, in Complex with GRB2:GAB1, Bind PI3K
PI3K Bound to Phosphorylated Heterodimers of ERBB2 ECD Mutants and EGFR Converts PIP2 to PIP3
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