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SIRT6 Deacetylates Histones at NOTCH1 and NOTCH4 Gene Promoters

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9604829).

Statements about SIRT6 Deacetylates Histones at NOTCH1 and NOTCH4 Gene Promoters

Part Of

Pre-NOTCH Transcription and Translation

Exact Match

https://identifiers.org/reactome:R-H ...

Instance Of

Biological Process
Negative Regulation of Gene Expression

Has Part(s)

NAD(1−)
Object of Statement Has Role
:
Reactant
Unnamed
: 1
SIRT6:Nucleosome(H3K9ac):NOTCH1,NOTCH4 Gene [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
2''-O-Acetyl-ADP-D-Ribose
Object of Statement Has Role
:
Product
Unnamed
: 1
SIRT6:Nucleosome:NOTCH1,NOTCH4 Gene [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
SIRT6:Nucleosome(H3K9ac):NOTCH1,NOTCH4 Gene [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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