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Peroxisomal Protein Import - Ontify
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Peroxisomal Protein Import
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9033241).
Statements about
Peroxisomal Protein Import
Has Part(s)
20 items
PEX2:PEX10:PEX12 Monoubiquitinates PEX5S,L at Cysteine-11
PEX2:PEX10:PEX12 Binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3
PEX5S,L Binds Cargo Proteins Containing PTS1
PEX5S,L:Cargo Binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
Cargo of PEX5S,L Translocates From the Cytosol to the Peroxisomal Matrix
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 Binds PEX1:PEX6:PEX26 and ZFAND6
PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 Dissociates Yielding Cytosolic Ub:PEX5S,L and Membrane PEX14:PEX13:PEX2:PEX10:PEX12
USP9X Binds Ub:PEX5S
PEX7 Binds Cargo Proteins Containing PTS2
PEX5L:PEX7:Cargo Binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
PEX5L Binds PEX7:Cargo Protein
USP9X Hydrolyzes Ub:PEX5S Yielding PEX5S and Ubiquitin
Cargo of PEX5L:PEX7 Translocates From the Cytosol to the Peroxisomal Matrix
PEX2:PEX10:PEX12 Monoubiquitinates PEX5L at Cysteine-11
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 Binds PEX1:PEX6:PEX26 and ZFAND6
PEX2:PEX10:PEX12 Binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3
PEX1:PEX6:PEX26:ZFAND6 Dissociates Ub:PEX5L and PEX7 From PEX14:PEX13:PEX2:PEX10:PEX12 and Translocates PEX5L and PEX7 From the Peroxisomal Membrane to the Cytosol
USP9X Binds Ub:PEX5L
USP9X Hydrolyzes Ub:PEX5L Yielding PEX5L and Ubiquitin
TYSND1 Cleaves Peroxisomal Proteins
Instance Of
Biological Pathway
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
Protein Localization
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