Ontify

⌘S

Biosynthesis of Electrophilic Ω-3 PUFA Oxo-Derivatives - Ontify

Biosynthesis of Electrophilic Ω-3 PUFA Oxo-Derivatives

Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9027604).

Statements about Biosynthesis of Electrophilic Ω-3 PUFA Oxo-Derivatives

Powered by

Has Part(s)

20 items

Dehydrogenase Dehydrogenates 13-HDHA to 13-Oxo-DHA

PTGS2 Dimer Oxidises DHA to 13-HDHA

Ac-PTGS2 Dimer Oxidises DHA to 17-HDHA (Macrophages)

Dehydrogenase Dehydrogenates 17-HDHA to 17-Oxo-DHA

ALOX5 Oxidises DHA to 7-HDHA

5-HEDH Dehydrogenates 7-HDHA to 7-Oxo-DHA

Oxo-DHAs Translocate From Cytosol to Extracellular Region

Ac-PTGS2 Dimer Oxidises DPAn-3 to 17-HDPAn-3

Dehydrogenase Dehydrogenates 17-HDPAn-3 to 17-Oxo-DPAn-3

Dehydrogenase Dehydrogenates 13(R)-HDPAn-3 to 13-Oxo-DPAn-3

ALOX5 Oxidises DPAn-3 to 7-HDPAn-3

5-HEDH Dehydrogenates 7-HDPAn-3 to 7-Oxo-DPAn-3

Oxo-DPAn-3s Translocate From Cytosol to Extracellular Region

ALOX5 Oxidises EPA to 5-HEPE

5-HEDH Dehydrogenates 5-HEPE to 5-Oxo-EPA

PTGS2 Dimer Oxidises EPA to PGH3

PGH3 Spontaneously Dehydrates to PGJ3

PGJ3 Isomerises to Δ12-PGJ3

Δ12-PGJ3 Spontaneously Dehydrates to 15d-PGJ3

5-Oxo-EPA, 15d-PGJ3 Translocate From Cytosol to Extracellular Region

Instance Of

Biological Pathway

Long-Chain Fatty Acid Biosynthetic Process

Exact Match

https://identifiers.org/reactome:R-H ...

Part Of

Biosynthesis of Specialized Proresolving Mediators (SPMs)