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Interleukin-23 Signaling
Instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-9020933).
Statements about
Interleukin-23 Signaling
Has Part(s)
12 items
IL12B Binds IL23A
IL12B:IL23A Translocates From ER Lumen to Extracellular Space
IL23R Binds JAK2
Interleukin-23 Binds Interleukin-23 Receptor
JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 Are Phosphorylated
IL23R in IL23:IL23 Receptor Complex Is Phosphorylated
STAT3 Binds to P-Y-IL23R in IL23:IL23 Receptor
STAT4 Binds P-Y-IL23R in IL23:IL23 Receptor
STAT3, STAT4 Are Phosphorylated by P-JAK2, P-TYK2 in IL23:IL23 Receptor
P-Y693-STAT4, P-Y705-STAT3 Dissociate From IL23:IL23 Receptor
P-Y705-STAT3 Binds P-Y693-STAT4
P-Y705-STAT3:p-Y693-STAT4 Translocates to the Nucleus
Instance Of
Biological Pathway
Interleukin-23-Mediated Signaling Pathway
Exact Match
https://identifiers.org/reactome:R-H ...
Part Of
Interleukin-12 Family Signaling
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