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PTPN18 Dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 - Ontify
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PTPN18 Dephosphorylates ERBB2 at Y1196, Y1112 and Y1248
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8864125).
Statements about
PTPN18 Dephosphorylates ERBB2 at Y1196, Y1112 and Y1248
Instance Of
Biological Process
Negative Regulation of ERBB Signaling Pathway
Part Of
Downregulation of ERBB2 Signaling
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
Water
Hydrogen Phosphate Ion
Object of Statement Has Role
:
Reactant
Unnamed
:
3
Object of Statement Has Role
:
Product
Unnamed
:
3
Phosphorylated ERBB2:EGFR Heterodimers:PTPN18 [Plasma Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
Phosphorylated ERBB2:EGFR Heterodimers:PTPN18 [Plasma Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
Phosphorylated ERBB2(dephosphorylated at Y1196,Y1112 and Y1248):EGFR Heterodimers:PTPN18 [Plasma Membrane]
Object of Statement Has Role
:
Product
Unnamed
:
1