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STING Recruits TBK1 and IRF3

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1834939).

Statements about STING Recruits TBK1 and IRF3

Instance Of

Biological Process

Part Of

IRF3-Mediated Induction of Type I IFN

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

13 items
Interferon Regulatory Factor 3
Object of Statement Has Role
:
Reactant
Unnamed
: 2
STING:STING [Cytoplasmic Vesicle Membrane]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
TANK Binding Kinase 1
Object of Statement Has Role
:
Reactant
Unnamed
: 2
MRE11:dsDNA [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
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STING:cGAMP [Cytoplasmic Vesicle Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
STING:TBK1:IRF3 [Cytoplasmic Vesicle Membrane]
Object of Statement Has Role
:
Product
Unnamed
: 1
DNA-PK:microbial dsDNA [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
DDX41:DDX41 Ligand [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
DDX41:c-Di-AMP, C-Di-GMP [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
TREX1 Dimer [Endoplasmic Reticulum Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
DsDNA:IFI16 [Cytosol]
Object of Statement Has Role
:
Modifier
Unnamed
: 1
NLR Family CARD Domain Containing 3
Object of Statement Has Role
:
Modifier
Unnamed
: 1
STING:c-Di-GMP [Cytoplasmic Vesicle Membrane]
Object of Statement Has Role
:
Modifier
Unnamed
: 1