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POLK and POLZ Cooperate in Elongation of Mispaired Primer Termini
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5655965).
Statements about
POLK and POLZ Cooperate in Elongation of Mispaired Primer Termini
Part Of
Translesion Synthesis by POLK
Instance Of
Biological Process
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
2'-Deoxyribonucleoside Triphosphate
Object of Statement Has Role
:
Reactant
Unnamed
:
10
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
:
1
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
:
1
POLZ [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
:
1
REV1 DNA Directed Polymerase
Object of Statement Has Role
:
Product
Unnamed
:
1
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
:
1
Diphosphate(3−) Anion
Object of Statement Has Role
:
Product
Unnamed
:
10