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KDM6B Demethylates H3K27me3 on P16INK4A Promoter

Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-3222593).

Statements about KDM6B Demethylates H3K27me3 on P16INK4A Promoter

Part Of

Oxidative Stress Induced Senescence

Instance Of

Biological Process

Exact Match

https://identifiers.org/reactome:R-H ...

Has Part(s)

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Succinate Dianion
Object of Statement Has Role
:
Product
Unnamed
: 3
2-Oxoglutarate(2-)
Object of Statement Has Role
:
Reactant
Unnamed
: 3
CDKN2A Gene:Nucleosome [Nucleoplasm]
Object of Statement Has Role
:
Product
Unnamed
: 1
CDKN2A Gene:H3K27Me3-Nucleosome [Nucleoplasm]
Object of Statement Has Role
:
Reactant
Unnamed
: 1
KDM6B:Fe2+ [Nucleoplasm]
Object of Statement Has Role
:
Modifier
Unnamed
: 1