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Cytosolic PHD2,3 Hydroxylates Proline Residues on HIF1A - Ontify
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Cytosolic PHD2,3 Hydroxylates Proline Residues on HIF1A
Instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1234177).
Statements about
Cytosolic PHD2,3 Hydroxylates Proline Residues on HIF1A
Part Of
Oxygen-Dependent Proline Hydroxylation of Hypoxia-Inducible Factor Alpha
Instance Of
Biological Process
Exact Match
https://identifiers.org/reactome:R-H ...
Has Part(s)
2-Oxoglutarate(2-)
Hypoxia Inducible Factor 1 Subunit Alpha
Dioxygen
2xHP-HIF1A [Cytosol]
Carbon Dioxide
Succinate Dianion
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [Cytosol]
Object of Statement Has Role
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Reactant
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2
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1
Object of Statement Has Role
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Reactant
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2
Object of Statement Has Role
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Product
Unnamed
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1
Object of Statement Has Role
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Product
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2
Object of Statement Has Role
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2
Object of Statement Has Role
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Modifier
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1